NEUTRALIZATION OF ARUBA RATTLESNAKE (CROTALUS UNICOLOR) VENOM ACTIVITY USING A POLYVALENT (ANTI-VIPERIDAE) VENEZUELAN ANTIVENIN
Autores/as
Alexis Rodríguez Acosta
Universidad Central de Venezuela, Instituto de Medicina Tropical, Sección de
Inmunoquímica, Caracas, Venezuela.Apartado 47423, Caracas 1041, Venezuela.
Luis F. Navarrete
Universidad Central de Venezuela, Instituto de Medicina Tropical, Sección de
Inmunoquímica, Caracas, Venezuela.Apartado 47423, Caracas 1041, Venezuela.
Crotalus unicolor is a endemic species of the Neotropical rattlesnakes, which it is only found on the Island of Aruba, located off the coast of Venezuela. In a comparative study using SDS-PAGE C. unicolor venom has similar bands as several Venezuelan rattlesnake venoms. At least 6 different bands of approximately 210, 116, 114, 110, 96 and 52 kDa were shared among C. unicolor and other Venezuelan rattlesnakes tested. Precipitation lines in an immunodiffusion assay exhibited many antigen-antibodies determinants in venom proteins and antivenin.
