NEUTRALIZATION OF ARUBA RATTLESNAKE (CROTALUS UNICOLOR) VENOM ACTIVITY USING A POLYVALENT (ANTI-VIPERIDAE) VENEZUELAN ANTIVENIN

Autores/as

  • Alexis Rodríguez Acosta Universidad Central de Venezuela, Instituto de Medicina Tropical, Sección de Inmunoquímica, Caracas, Venezuela.Apartado 47423, Caracas 1041, Venezuela.
  • Luis F. Navarrete Universidad Central de Venezuela, Instituto de Medicina Tropical, Sección de Inmunoquímica, Caracas, Venezuela.Apartado 47423, Caracas 1041, Venezuela.

Palabras clave:

Crotalus unicolor, Aruba rattlesnake, antivenin, venom, rattlesnake ecology.

Resumen

Crotalus unicolor  is a endemic species of the Neotropical rattlesnakes, which it is only found on the Island of Aruba, located off the coast of Venezuela. In a comparative study using SDS-PAGE C. unicolor venom has similar bands as several Venezuelan rattlesnake venoms. At least 6 different bands of approximately 210, 116, 114, 110, 96 and 52 kDa were shared among C. unicolor  and other Venezuelan rattlesnakes tested. Precipitation lines in an immunodiffusion assay exhibited many antigen-antibodies determinants in venom proteins and antivenin.

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Número

Vol. 21 Núm. 1 (2001)

Sección

Artículos y Revisiones