The role of neutrophil-lymphocyte ratio in patients with chronic obstructive pulmonary disease in Babylon province

Resumen

Introduction: Chronic obstructive pulmonary disease (COPD) is a complex illness, associated with many comorbidities, it is usually misdiagnosed and underrated, the aim of study is to regulate whether neutrophil lymphocyte ratio (NLR) can be used in diagnosis of COPD. Method: Comparative cross sectional study, the data was conducted between 1 December 2019 and 1 March 2020 among patients with approved diagnosis of AECOPD and attendees to emergency unit and respiratory outpatient clinic or admitted to general word and intensive care unit. The attendees to emergency unit and respiratory outpatient clinic or admitted to general word and intensive care unit were asked to participate in this study and sample size of 79 patients were included in this study. Other 79 healthy persons they attended emergency unit as relative to patients were selected as the control group. Results: Comparative cross sectional study of 79 patients with COPD and 79 patients normal, mean ± SD of age (66 ±10) years old and N/L ratio (5.9 ± 4.8), according to fig (1); (45.57%) of patients with COPD have sever FEV1 and (30.38%) of patients have moderate FEV1. In addition, fig (2) show 73% of patients in current study are males and 27% are females with 71% are old age (more than 60 years old). There is significant difference between NLR of patients with COPD and normal patients, increase in NLR occur in patients with COPD. Conclusion: NLR may beneficial inflammation predictor in diagnosis COPD and its acute exacerbation.