Cromoendoscopia virtual utilizando BLI en el diagnóstico endoscópico de esófago de Barrett neoplásico y no neoplásico

Autores/as

  • Juan Carlos González Gastroenterólogo. Facultad de Medicina. Universidad Central de Venezuela. Clínica El Ávila. Caracas-Venezuela.

Palabras clave:

Barrett, BLI, BLINC, diagnóstico endoscópico, cromoendoscopia virtual

Resumen

Introducción: Al ser el esófago de Barrett la única lesión precursora conocida para el desarrollo del Adenocarcinoma de esófago, es importante en su diagnóstico establecer si es Neoplásico o No Neoplásico. Objetivo: El objetivo fue evaluar la eficiencia de la Cromoendoscopia Virtual utilizando Blue Laser Imaging (BLI), para el diagnóstico endoscópico de Esófago de Barrett Neoplásico y no Neoplásico. Materiales y Métodos: Estudio observacional prospectivo no probabilístico de tipo intencional, se incluyeron 91 pacientes, los hallazgos endoscópicos a buscar fueron las alteraciones morfológicas endoscópicas que muestran los descriptores predictores de la Clasificación BLINC, usando Cromoendoscopia Virtual basada en BLI, para identificar el Esófago de Barrett Neoplásico o No Neoplásico, con su confirmación histopatológica. Resultados: 91 pacientes, el promedio de edad 57 años (DE = 13.4), 55 (60,44%) mujeres y 35 (39,56%) hombres.  Esófago de Barrett Neoplásico: 16 pacientes con diagnóstico endoscópico Sensibilidad: 93.75%, Especificidad: 96%, VPP: 84%, VPN: 89%. Kappa: 0.85, p<0.001.  Esófago de Barrett No Neoplásico:  75 pacientes con diagnostico endoscópico Sensibilidad: 95.50%. Especificidad: 93%, VPP: 98%, VPN: 85%. Kappa: 0,86, p<0.001. Conclusión: La alta sensibilidad obtenida es un fuerte indicador del desempeño de la Cromoendoscopia Virtual utilizando BLI, para ser usada eficazmente en el diagnóstico de Esófago de Barrett Neoplásico o No Neoplásico.

Descargas

Los datos de descargas todavía no están disponibles.

Citas

- Jung KW, Talley NJ, Romero Y et al. Epidemiology and natural history of intestinal metaplasia of thegastroesophageal junction and Barrett's esophagus: a population-based study. Am J Gastroenterol 2011; 106:1447–1455. doi: 10.1038/ajg.2011.130

- Sampliner RE. Practice guidelines on the diagnosis, surveillance, and therapy of Barrett's esophagus. The Practice ParametersCommittee of the American College of Gastroenterology. Am J Gastroenterol. 1998; 93 (7): 1028-1032. doi: 10.1111/j.1572-0241.1998.00362

- Spechler SJ, Sharma P, Souza R.F. et al. American Gastroenterological Association medical position statement on the management of Barrett's esophagus. Gastroenterology 2011; 140:1084-91. doi: 10.1053/j.gastro.2011.01.030

- Hur C, Miller M, Kong CY, et al. Trends in esophageal adenocarcinoma incidence and mortality. Cancer 2013; 119:1149-58. doi: 10.1002/cncr.27834

- Fitzgerald RC, Di Pietro M, Ragunath K, et al. British Society of Gastroenterology guidelines on the diagnosis and management of Barrett's oesophagus. Gut. 2014; 63:7–42. doi: 10.1136/gutjnl-2013-305372

- 6- Shaheen NJ, Falk GW, Iyer PG, et al. ACG Clinical Guideline: Diagnosis and Management of Barrett’s Esophagus. American Journal of Gastroenterolog. 2016;111(1):30-50. doi: 10.1038/ajg.2015.322

- Qumseya B, Sultan S, Bain P, et al. ASGE guideline on screening and surveillance of Barrett’s Esophagus. Gastrointestinal Endoscopy. 2019;90(3):339-359. doi: 10.1016/j.gie.2019.05.012

Corley DA, Kubo AI, DeBoer J, et al. Diagnosing Barrett’s esophagus: reliability of clinical and pathologic diagnoses. Gastrointest Endosc. 2009 May; 69(6): 1004–1010. doi: 10.1016/j.gie.2008.07.035

Cjalasani N, Wo JM, Hunter JG, et al. Significance of intestinal metaplasia in different areas of esophagus including esophagogastric junction Dig Dis Sci 1997; 42:603-607. doi: 10.1023/a:1018863529777

- Sharma P, McQuaid K, Dent J, et al. A critical review of the diagnosis and management of Barrett’s esophagus: the AGA Chicago workshop. Gastroenterology 2004; 127:310–30. doi: 10.1053/j.gastro.2004.04.010

-11- Kariv R, Plesec TP, Goldblum JR, et al. The Seattle protocol does not more reliably predict the detection of cancer at the time of esophagectomy than a less intensive surveillance protocol. Clin Gastroenterol Hepatol 2009; 7:653–8. doi: 10.1016/j.cgh.2008.11.024

-Abrams JA, Kapel RC, Lindberg GM, et al. Adherence to biopsy guidelines for Barrett’s esophagus surveillance in the community setting in the United States. Clin Gastroenterol Hepatol 2009; 7:736–42. doi: 10.1016/j.cgh.2008.12.027

- Sampliner RE Updated guidelines for the diagnosis, surveillance, and therapy of Barrett's esophagus. Am J Gastroenterol. 2002; 97(8):1888-1895. doi: 10.1111/j.1572-0241.2002. 05910.x

- Woolf GM, Riddell RH, Robert H, et al. Gastroeintestinal Endoscopy 1989; 35:541-544. DOI: 10.1016/s0016-5107(89)72907-2. doi: 10.1016/s0016-5107(89)72907-2

-Canto MI, Setrakian S, Petras R, et al. Gastrointestinal Endoscopy 1996; 44:1-7. DOI: 10.1016/s0016-5107(96)70221-3. doi: 10.1016/s0016-5107(96)70221-3

. Canto MI, Setrakian S, Willis J, et al. Gastrointestinal Endoscopy 2000:51:560-568. doi: 10.1016/s0016-5107(00)70290-2

- Reyes AA. Nuevas técnicas de imagen (iSCAN, NBI, FICE). Rev Gastroenterol Mex. 2011;76 Supl 1:134-136.

- Silva FB, Dinis-Ribeiro M, Vieth M, et al. Endoscopic assessment and grading of Barrett’s esophagus using magnification endoscopy and narrow-band imaging: Accuracy and interobserver agreement of different classification systems. Gastrointest Endosc. 2011; 73:7–14. doi: 10.1016/j.gie.2010.09.023

-. Qumseya BJ, Wang H, Badie N, et al. Advanced imaging technologies increase detection of dysplasia and neoplasia in patients with barrett’s esophagus: A meta-analysis and systematic review. Clinical Gastroenterology and Hepatology. 2013.Dec;11(12):1562-70. doi: 10.1016/j.cgh.2013.06.017

- Subramanian V, Ragunath K, Hirchowitz BI, et al. Advanced endoscopic imaging: a review of commercially available technologies. Clin Gastroenterol Hepatol. 2014;12(3):368–76. doi: 10.1016/j.cgh.2013.06.015

Sano Y, Kobayashi M, Hamamoto Y, et al. New diagnostic method based on color imaging using narrow band imaging (NBI) system for gastrointestinal tract. DDW Atlanta 2001 [abstract]: A696.

Gono K, Yamaguchi M, Ohyama N. Improvement of image quality of the electroendoscopy by narrowing spectral shapes of observation light. In: Imaging Society of Japan. Proceedings of International Congress Imaging Science, May 13-17, Tokyo, Japan: Imaging Society of Japan, 2002: 399-400.23.

- Shinya K, Fujishiro M. Novel image-enhanced endoscopy with i-scan technology. World Journal of Gastroenterology, 2010; 16(9): 1043-1049. doi: 10.3748/wjg. v16.i9.1043

Gono K, Oby T, Yamaguchi M, et al. Appearance of enhanced tissue features in narrow band endoscopic imaging. Journal of Biomedical Optic 2004; 9(3):568-577. doi: 10.1117/1.1695563

- Miyake Y KT, Takeuchi S, Tsumura N, et al. Development of new electronic endoscopes using the spectral images of an internal organ. In: Proceedings of the IS&T/SID’s Thirteen Color Imaging Conference, 2005. Scottsdale, Ariz; 2005. 261-269.

Osawa H, Yamamoto H. Present and future status of flexible spectral imaging co or enhancement and blue laser imaging technology. Dig Endosc. 2014 Jan; 26 Suppl 1:105-15. doi: 10.1111/den.12205l

Osawa H, Miura Y, Takezawa T, et al. Linked color images and blue laser for the detection of the upper gastrointestinal tract. Clin Endosc 2018; 51: 513-526. doi: 10.5946/ce.2018.132

ASGE Technology Committee; Thosani N, Abu Dayyeh BK, Sharma P, et al. ASGE Technology Committee systematic review and metaanalysis assessing the ASGE Preservation and Incorporation of Valuable Endoscopic Innovations thresholds for adopting real-time imaging-assisted endoscopic targeted biopsy during endoscopic surveillance of Barrett’s esophagus. Gastrointest Endosc 2016; 83:684-98. doi: 10.1016/j.gie.2016.01.007

Subramaniam S, Kandiah K, Schoon E, et al. Development and validation of the international blue-light imaging for Barrett's neoplasia classification. Gastrointestinal Endoscopy.2022;91(2): 310-320. doi: 10.1016/j.gie.2019.09.035

Singh R, Anagnostopoulos GK, Yao K, et al. Narrow-band imaging with magnification in Barrett’s esophagus: Validation of a simplified grading system of mucosal morphology patterns against histology. Endoscopy. 2008; 40:457–63. doi: 10.1055/s-2007-995741

Kara MA, Ennahachi M, Fockens P, et al. Detection and classification of the mucosal and vascular patterns (mucosal morphology) in Barrett’s esophagus by using narrow band imaging. Gastrointest Endosc. 2006; 64(2):155-166. doi: 10.1016/j.gie.2005.11.049

Sharma P, Bansal A, Mathur S, et al. The utility of a novel narrow band imaging endoscopy system in patients with Barrett’s esophagus. Gastrointest Endosc. 2006; 64:167–75. doi: 10.1016/j.gie.2005.10.044

Baldaque-Silva F, Marques M, Lunet N, et al. Endoscopic assessment and grading of Barrett’s esophagus using magnification endoscopy and narrow band imaging: Impact of structured learning and experience on the accuracy of the Amsterdam classification system. Scand J Gastroenterol. 2013; 48:160–167. doi: 10.3109/00365521.2012.746392

Lipman G, Bisschops R, Sehgal V, et al. Systematic assessment with I-SCAN magnification endoscopy and acetic acid improves dysplasia detection in patients with Barrett’s esophagus. Endoscopy. 2017; 49:1219–1228. doi: 10.1055/s-0043-113441

González JC, Ruiz ME. Atlas de Imágenes Endoscópicas FICE. Editorial Versilia. 2009.

González JC, Dos Reis V. Esófago de Barrett y Cromoscópia Electronica. Gen 2016;70(3):71-75.

González JC, Del Monte R. Atlas de Imágenes Endoscópicas BLI/LCI. Editorial Bell-Tech. 2020.

Goldblum JR. Controversies in the diagnosis of Barrett esophagus and Barrett-related dysplasia: one pathologist's perspective. Arch Pathol Lab Med. 2010; 134:1479-1484. doi: 10.5858/2010-0249-RA.1

Duits L, Phoa KN, Curvers WL, et al. Barrett's oesophagus patients with low-grade dysplasia can be accurately risk-stratified after histological review by an expert pathology panel. Gut.2015;64(5):700-706. doi: 10.1136/gutjnl-2014-307278

Prashanth V, Vijay K, John G, et al. Discordance Among Pathologists in the United States and Europe in Diagnosis of Low-grade Dysplasia for Patients With Barrett's Esophagus. Gastroenterology. 2017;152(3):564-570. doi: 10.1053/j.gastro.2016.10.041

Descargas

Publicado

2024-03-27

Cómo citar

González, J. C. (2024). Cromoendoscopia virtual utilizando BLI en el diagnóstico endoscópico de esófago de Barrett neoplásico y no neoplásico. Revista GEN, 77(4), 140–147. Recuperado a partir de http://saber.ucv.ve/ojs/index.php/rev_gen/article/view/28198

Número

Sección

ARTÍCULO ORIGINAL