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Título : First Description of Endemic HTLV-II Infection Among Venezuelan Amerindians
Autor : Echeverria de Perez, Gloria
Leon-Ponte, Matilde
Noya, Oscar
Botto, Carlos
Gallo, Dana
BIANCO COLMENARES, NICOLÁS E.
Palabras clave : HTLV-II
Amerindians
Pume
Yaruro
enzyme immunoassays
infected cell
Fecha de publicación : 1993
Editorial : Journal of Acquired Immune Deficiency Syndromes
Citación : Vol. 6;No. 12 pp 1368-1372
Resumen : We describe for the first time the presence of human T lymphotropic virus type II (HTLV-II) infection in Venezuela, among the Pume Amerindians living in the southern plains of the country. Antibodies to HTLV-II antigens were assessed by enzyme immunoassays (Elisa), Western blot, radioimmuno-precipitation, and immunofluorescence; titration studies against HTLV-I- and HTLV-II-infected cell lines were very useful in the differentiation of HTLV-I and HTLV-II antibodies. The HTLV-II general prevalence was 5%; however, there is a striking difference in prevalence between the truly isolated villages (0%) when compared to those living along the riverside and thus in contact with outsiders (9%). Preliminary evidence suggests sexual contact as the main source of transmission. These findings might suggest that HTLV-II in Venezuela originated through contact with outsiders rather than ancient infection related to the origins of the Pume.
URI : http://hdl.handle.net/123456789/14533
ISSN : 1525-4135
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