SABER UCV >
1) Investigación >
Artículos Publicados >

Por favor, use este identificador para citar o enlazar este ítem: http://hdl.handle.net/123456789/14462

Título : IMMUNOPATHOLOGY OF HUMAN SCHISTOSOMIASIS MANSONI. I. IMMUNOMODULATORY INFLUENCES ON T CELL FUNCTION.
Autor : ALDREY, O.
NOYA, B.
MACHADO, I.
NOYA, O.
Bianco Colmenares, Nicolás E.
PEREZ, G . E.
Palabras clave : Immunoregulatíon
T cells
Human schistosomiasis
Cell mediated immune response
chronic Schistosoma mansoni
mononuclear cells
cell preparations
precultured cells
Fecha de publicación : 1988
Editorial : Revista do Instituto de Medicina Tropical de São Paulo
Citación : Vol. 30;No. 6 pp 393-399
Resumen : Cell mediated immune response was studied in patients with recent and chronic Schistosoma mansoni infection. Precultured peripheral mononuclear cells showed significantly higher responses to S. mansoni adult worm antigen (SAWA) when corn pared to fresh cell preparations. The addition of each patient serum to the precultured cells reactions to SAWA or recall antigens demonstrated a strong inhibitory serum action, which was also noted on allogeneic cells derived from healthy subjects. The CD4 subset was the main responding cell t o SAWA being this reactivity highly suppressed by the presence of the monocyte-macrophage accessory cells. We stressed the simultaneous inhibitory action of humoral and cellular factors on the specific cell response to S. mansoni.
URI : http://hdl.handle.net/123456789/14462
ISSN : 1678-9946
Aparece en las colecciones: Artículos Publicados

Ficheros en este ítem:

Fichero Descripción Tamaño Formato
Documento 37.pdf32.54 MBAdobe PDFVisualizar/Abrir

Los ítems de DSpace están protegidos por copyright, con todos los derechos reservados, a menos que se indique lo contrario.

 

Valid XHTML 1.0! DSpace Software Copyright © 2002-2008 MIT and Hewlett-Packard - Comentarios