SABER UCV >
1) Investigación >
Artículos Publicados >

Por favor, use este identificador para citar o enlazar este ítem: http://hdl.handle.net/123456789/14060

Título : Biological activity of Guatteria cardoniana fractions
Autor : Paredes, A.
Hasegawa, Masahisa
Prieto, F.
Méndez, Jeannette
Rodríguez, María del C.
Rodríguez-Ortega, M.
Palabras clave : Annonaceae
Guatteria cardoniana
Antiviral
Sindbis virus
Fecha de publicación : 2001
Editorial : Journal of Ethno-Pharmacology
Citación : 78 (2001) 129–132
Resumen : Methanolic extract of leaves and twigs of Guatteria cardoniana R.E. Fries (Annonaceae), a plant from the Venezuelan rain forest, was separated in alkaloid rich fractions and their biological effect on baby hamster kidney (BHK) cell line was studied. The initial plant extract (FA) induced cell proliferation, cytotoxicity as well as antiviral activity, depending on the concentration used. Further separation of this methanolic extract allowed us to separate these biological activities. The fraction with the highest antiviral activity (F7) was chromatographed and three of the nine alkaloid-rich fractions obtained, retained this activity. One of them (F711) exhibited the highest inhibitory effect against a neurotropic Sindbis virus (NSV).
URI : http://hdl.handle.net/123456789/14060
ISSN : 0022-3573
Aparece en las colecciones: Artículos Publicados

Ficheros en este ítem:

Fichero Descripción Tamaño Formato
Biological activity of Guatteria cardoniana fractions.pdf114.76 kBAdobe PDFVisualizar/Abrir

Los ítems de DSpace están protegidos por copyright, con todos los derechos reservados, a menos que se indique lo contrario.

 

Valid XHTML 1.0! DSpace Software Copyright © 2002-2008 MIT and Hewlett-Packard - Comentarios