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Por favor, use este identificador para citar o enlazar este ítem: http://hdl.handle.net/123456789/13946

Título : Cell-Mediated Effector Mechanisms in Aging Humans
Autor : Marcano, Norka B.
Rivas, Alberto
Feo F., Elizabeth
Blanca, Isaac
Penchaszadeh, Graciela K.
Pérez-Rojas, Gloria
Bianco Colmenares, Nicolás E.
Palabras clave : Specific
nonspecific
alloantigens
Tckiller cells
cell-mediated Iympholysis
RhD+
Fecha de publicación : 1982
Editorial : lnternational Archives of Allergy and Applied Immunology
Citación : Vol.69;Nº 1 pag. 7-11
Resumen : Specific and nonspecific cell-mediated effector mechanisms have been simultaneously assayed in 15 aged humans. 8 were female and 7 male, including a 114-year-old male in remarkably good health. Proliferative response to alloantigens, the generation of T killer cells and the ability to express cell-mediated Iympholysis as well as the presence of natural cell-mediated cytotoxicity against K562 tumor cell line and the capacity to mount an ADCC response to RhD+ human red blood cell sensitized with anti-D antisera, revealed that in the human aged, while T function significantly declines, nonspecific cell mediated effector mechanisms are operative.
URI : http://hdl.handle.net/123456789/13946
ISSN : 0020-5915
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