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Título : Serum adipokine levels in patients with systemic lupus erythematosus
Autor : De Sanctis, Juan B.
ZABALETA, MERCEDES
Bianco Colmenares, Nicolás E.
RIVAS, LILIANA
Garmendia, Jenny V.
Palabras clave : Adipokines
leptin
adiponectin
ghrelin
resistin
visfatin
Fecha de publicación : 2009
Editorial : Autoimmunity
Citación : VOL. 42;4
Resumen : In patients with systemic lupus erythematosus (SLE) metabolic alterations are often observed, which may be due to either the disease, the genetic background or the treatment. We studied the serum levels of the adipokines leptin, adiponectin, resistin, visfatin and ghrelin in patients with SLE and controls. Leptin levels were lower and adiponectin, ghrelin and visfatin levels were higher in the patients. No significant differences were encountered for resistin. The values of adipokines were independent of treatment, even after correction for body mass index. Inverse correlations were found among leptin and adiponectin, ghrelin and visfatin. We conclude that adipokines are involved in the metabolic imbalance of patients with SLE.
URI : http://saber.ucv.ve/jspui/handle/123456789/12119
ISSN : 0891-6934
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