SABER UCV >
1) Investigación >
Artículos Publicados >
Por favor, use este identificador para citar o enlazar este ítem:
http://hdl.handle.net/10872/7266
|
Título : | Trypanosoma cruzi III from armadillos (Dasypus novemcinctus novemcinctus) from Northeastern Venezuela and its biological behavior in murine model. Risk of emergency of Chagas’ disease |
Autor : | Morocoima, Antonio Carrasco, Hernan Herrera, Leidi Boadas, Johanna Chique, Jose |
Palabras clave : | Armadillo (Dasypus novemcinctus TcIII PCR–RFLP Venezuela |
Fecha de publicación : | 1-Aug-2012 |
Editorial : | Elsevier. Experimental Parasitology |
Citación : | Experimental Parasitology 132 (2012) 341–347 |
Resumen : | Trypanosoma cruzi, etiological agent of Chagas’ disease, was isolated from armadillos (Dasypus novemcinctus
novemcinctus) captured in rural communities Northeastern Venezuela from Nueva Esparta State (no
endemic for Chagas’ disease), Monagas and Anzoátegui States (endemics). The isolates, genetically typed
by PCR–RFLP as belonging to the TcIII DTU, have demonstrated in murine model heterogenic parasitemia,
mortality and histotropism with marked parasitism in cardiac, skeletal, and smooth myocytes that
showed correlation with lymphobasophilic inflammatory infiltrates. Our finding of T. cruzi infected armadillos
in Isla Margarita (Nueva Esparta State), together with reports of triatomine vectors in this region,
the accentuated synanthropy of armadillos, intense economic activity, migration due to tourism and the
lack of environmental education programs all of them represent risks that could cause the emergence of
Chagas’ disease in this area. This is the first report of the TcIII DTU in Northeastern Venezuela, thus widening
the geographic distribution of this DTU. |
URI : | http://hdl.handle.net/10872/7266 |
Aparece en las colecciones: | Artículos Publicados
|
Los ítems de DSpace están protegidos por copyright, con todos los derechos reservados, a menos que se indique lo contrario.
|