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http://hdl.handle.net/10872/13946
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| Título : | Cell-Mediated Effector Mechanisms in Aging Humans |
| Autor : | Marcano, Norka B.
Rivas, Alberto
Feo F., Elizabeth
Blanca, Isaac
Penchaszadeh, Graciela K.
Pérez-Rojas, Gloria
Bianco Colmenares, Nicolás E. |
| Palabras clave : | Specific
nonspecific
alloantigens
Tckiller cells
cell-mediated Iympholysis
RhD+ |
| Fecha de publicación : | 1982 |
| Editorial : | lnternational Archives of Allergy and Applied Immunology |
| Citación : | Vol.69;Nº 1 pag. 7-11 |
| Resumen : | Specific and nonspecific cell-mediated effector mechanisms have been simultaneously assayed in 15 aged humans. 8 were female and 7 male, including a 114-year-old male in remarkably good health. Proliferative response to alloantigens, the generation of T killer cells and the ability to express cell-mediated Iympholysis as well as the presence of natural cell-mediated cytotoxicity against K562 tumor cell line and the capacity to mount an ADCC response to RhD+ human red blood cell sensitized with anti-D antisera, revealed that in the human aged, while T function significantly declines, nonspecific cell mediated effector mechanisms are operative. |
| URI : | http://hdl.handle.net/10872/13946 |
| ISSN : | 0020-5915 |
| Aparece en las colecciones: | Artículos Publicados
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